This grand tableau of human relations and interaction qualifies as the artist’s masterpiece. An early pupil of Rembrandt in Leiden, Lesire must have maintained access to the master’s studio, as he adapted a drawing of the early 1640s for his theme and figural arrangement in this painting. In a moving touch, he emphasizes Tobit’s flinching as the salve is applied to his eyes, in keeping with the description of this detail in the Dutch States Bible translation of the text.